HMM Summary Page: TIGR02033

AccessionTIGR02033
NameD-hydantoinase
Functiondihydropyrimidinase
Gene SymbolhydA
Trusted Cutoff393.25
Domain Trusted Cutoff393.25
Noise Cutoff322.65
Domain Noise Cutoff322.65
Isology Typeequivalog
EC Number3.5.2.2
HMM Length454
Gene Ontology TermGO:0004157: dihydropyrimidinase activity molecular_function
GO:0008152: metabolic process biological_process
AuthorSelengut J
Entry DateOct 20 2003 5:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the D-hydantoinase (dihydropyrimidinase) which primarily converts 5,6-dihydrouracil to 3-ureidopropanoate but also acts on dihydrothymine and hydantoin. The enzyme is a metalloenzyme [1].
ReferencesRN [1] RM PMID: 7765480 RT A thermostable hydantoinase of Bacillus stearothermophilus NS1122A: cloning, sequencing, and high expression of the enzyme gene, and some properties of the expressed enzyme. RA Mukohara Y, Ishikawa T, Watabe K, Nakamura H. RL Biosci Biotechnol Biochem. 1994 Sep;58(9):1621-6. DR HAMAP; MF_01644; 9 of 10