Accession | TIGR01929 |
Name | menB |
Function | naphthoate synthase |
Gene Symbol | menB |
Trusted Cutoff | 342.70 |
Domain Trusted Cutoff | 342.70 |
Noise Cutoff | 201.40 |
Domain Noise Cutoff | 201.40 |
Isology Type | equivalog |
EC Number | 4.1.3.36 |
HMM Length | 259 |
Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
Subrole Category | Menaquinone and ubiquinone |
Gene Ontology Term | GO:0008935: 1,4-dihydroxy-2-naphthoyl-CoA synthase activity molecular_function |
| GO:0009234: menaquinone biosynthetic process biological_process |
Author | Sunshine J |
Entry Date | Jul 17 2003 9:45AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. |
Genome Property | GenProp0058: menaquinone biosynthesis via SEPHCHC (HMM) |