| Accession | TIGR01848 |
| Name | PHA_reg_PhaR |
| Function | polyhydroxyalkanoate synthesis repressor PhaR |
| Gene Symbol | phaR |
| Trusted Cutoff | 109.45 |
| Domain Trusted Cutoff | 109.45 |
| Noise Cutoff | 52.35 |
| Domain Noise Cutoff | 52.35 |
| Isology Type | equivalog |
| HMM Length | 107 |
| Mainrole Category | Fatty acid and phospholipid metabolism |
| Subrole Category | Biosynthesis |
| Gene Ontology Term | GO:0006355: regulation of transcription, DNA-dependent biological_process |
| | GO:0016564: transcription repressor activity molecular_function |
| Author | Haft DH |
| Entry Date | Mar 10 2003 4:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Poly-B-hydroxyalkanoates are lipidlike carbon/energy storage polymers found in granular inclusions. PhaR is a regulatory protein found in general near other proteins associated with polyhydroxyalkanoate (PHA) granule biosynthesis and utilization. It is found to be a DNA-binding homotetramer that is also capable of binding short chain hydroxyalkanoic acids and PHA granules. PhaR may regulate the expression of itself, of the phasins that coat granules, and of enzymes that direct carbon flux into polymers stored in granules. The C-terminal region is poorly conserved in this family and is not part of this model.//GO terms added 12/6/04 [SS] |
| References | RN [1]
RM 12081972
RT A repressor protein, PhaR, regulates polyhydroxyalkanoate (PHA) synthesis via its direct interaction with PHA.
RA Maehara A, Taguchi S, Nishiyama T, Yamane T, Doi Y.
RL J Bacteriol 2002 Jul;184(14):3992-4002
RN [2]
RM 11914361
RT AniA regulates reserve polymer accumulation and global protein expression in Rhizobium etli.
RA Encarnacion S, del Carmen Vargas M, Dunn MF, Davalos A, Mendoza G, Mora Y, Mora J
RL J Bacteriol 2002 Apr;184(8):2287-95 |
| Genome Property | GenProp0055: polyhydroxyalkanoic acids (HMM) |
