HMM Summary Page: TIGR01769
| Accession | TIGR01769 |
| Name | GGGP |
| Function | phosphoglycerol geranylgeranyltransferase |
| Trusted Cutoff | 161.55 |
| Domain Trusted Cutoff | 161.55 |
| Noise Cutoff | 85.85 |
| Domain Noise Cutoff | 85.85 |
| Isology Type | equivalog |
| EC Number | 2.5.1.41 |
| HMM Length | 205 |
| Author | Selengut J |
| Entry Date | Dec 16 2002 3:59PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents geranylgeranylglyceryl phosphate synthase which catalyzes the first committed step in the synthesis of ether-linked membrane lipids in archaea [1]. The active enzyme is reported to be a homopentamer in Methanobacterium thermoautotrophicum but is reported to be a homodimer in Thermoplasma acidophilum. |
| References | RN [1] RM PMID: 11732904 RT Geranylgeranylglyceryl phosphate synthase. Characterization of the recombinant enzyme from Methanobacterium thermoautotrophicum. RA Soderberg T, Chen A, Poulter CD. RL Biochemistry 2001 Dec 11;40(49):14847-54 RN [2] RM 12801917 RT Purification and characterization of geranylgeranylglyceryl phosphate synthase from a thermoacidophilic archaeon, Thermoplasma acidophilum. RA Nemoto N, Oshima T, Yamagishi A. RL J Biochem (Tokyo). 2003 May;133(5):651-7. DR HAMAP; MF_00112; 40 of 94 |