| Accession | TIGR01719 |
| Name | euk_UDPppase |
| Function | uridine phosphorylase |
| Trusted Cutoff | 249.95 |
| Domain Trusted Cutoff | 249.95 |
| Noise Cutoff | 125.50 |
| Domain Noise Cutoff | 125.50 |
| Isology Type | equivalog |
| EC Number | 2.4.2.3 |
| HMM Length | 287 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Salvage of nucleosides and nucleotides |
| Gene Ontology Term | GO:0004731: purine-nucleoside phosphorylase activity molecular_function |
| | GO:0006139: nucleobase-containing compound metabolic process biological_process |
| Author | Selengut J |
| Entry Date | Oct 7 2002 11:04AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents a clade of mainly eucaryotic uridine phosphorylases. Genes from human [1] and mouse [2] have been characterized. This enzyme is a member of the PHP/UDP subfamily (PF01048) and is closely related to the bacterial uridine (TIGR01718) and inosine (TIGR00107) phosphorylase equivalogs. In addition to the eukaryotes, a gene from Mycobacterium leprae is included in this equivalog and may have resulted from lateral gene transfer. |
| References | RN [1]
RM PMID: 7488099
RT Cloning and expression of human uridine phosphorylase
RA Watanabe S.-I., Uchida T.
RL Biochem. Biophys. Res. Commun. 216:265-272(1995).
RN [1]
RM PMID: 7744869
RT Purification, cloning, and expression of murine uridine phosphorylase.
RA Watanabe S.-I., Hino A., Wada K., Eliason J.F., Uchida T.
RL J. Biol. Chem. 270:12191-12196(1995). |
