| Accession | TIGR01685 |
| Name | MDP-1 |
| Function | magnesium-dependent phosphatase-1 |
| Gene Symbol | MDP-1 |
| Trusted Cutoff | 53.75 |
| Domain Trusted Cutoff | 53.75 |
| Noise Cutoff | 36.15 |
| Domain Noise Cutoff | 36.15 |
| Isology Type | equivalog |
| HMM Length | 174 |
| Author | Selengut J |
| Entry Date | Sep 19 2002 3:55PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents two closely related clades of sequences from eukaryotes and archaea. The mouse enzyme has been characterized as a phosphatase and has been positively identified as a member of the haloacid dehalogenase (HAD) superfamily by site-directed mutagenesis of the active site residues [1,2]. |
| References | RN [1]
RM PMID: 11601995
RT MDP-1 is a new and distinct member of the haloacid dehalogenase family of aspartate-dependent phosphohydrolases.
RA Selengut, JD
RL Biochemistry 2001 Oct 23;40(42):12704-11
RN [2]
RM PMID: 10889041
RT MDP-1: A novel eukaryotic magnesium-dependent phosphatase.
RA Selengut JD, Levine RL.
RL Biochemistry. 2000 Jul 18;39(28):8315-24. |
