| Accession | TIGR01645 |
| Name | half-pint |
| Function | poly-U binding splicing factor, half-pint family |
| Trusted Cutoff | 443.95 |
| Domain Trusted Cutoff | 443.95 |
| Noise Cutoff | 206.55 |
| Domain Noise Cutoff | 206.55 |
| Isology Type | subfamily |
| HMM Length | 607 |
| Author | Selengut J |
| Entry Date | Aug 27 2002 1:33PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The proteins represented by this model contain three RNA recognition motifs (rrm: PF00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors [1,2,3].
In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA [2]. |
| References | RN [1]
RM PMID: 11879639
RT Half pint regulates alternative splice site selection in Drosophila.
RA Van Buskirk C, Schupbach T.
RL Dev Cell 2002 Mar;2(3):343-53
RN [2]
RM PMID: 10606266
RT PUF60: a novel U2AF65-related splicing activity.
RA Page-McCaw PS, Amonlirdviman K, Sharp PA.
RL RNA 1999 Dec;5(12):1548-60
RN [3]
RM PMID: 10668799
RT Interaction cloning and characterization of RoBPI, a novel protein binding to human Ro ribonucleoproteins.
RA Bouffard P, Barbar E, Briere F, Boire G.
RL RNA 2000 Jan;6(1):66-78 |
