| Accession | TIGR01545 |
| Name | YfhB_g-proteo |
| Function | HAD hydrolase, family IF |
| Gene Symbol | yfhb |
| Trusted Cutoff | 259.25 |
| Domain Trusted Cutoff | 259.25 |
| Noise Cutoff | 204.50 |
| Domain Noise Cutoff | 204.50 |
| Isology Type | hypoth_equivalog |
| HMM Length | 210 |
| Gene Ontology Term | GO:0016787: hydrolase activity molecular_function |
| Author | Selengut J |
| Entry Date | Jun 12 2002 10:39AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes a clade of sequences limited to the gamma proteobacteria. This group is a member of the haloacid dehalogenase (HAD) superfamily of aspartate-dependent hydrolases and all of the conserved catalytic motifs are present [1]. Although structurally similar to subfamily IA in that the variable domain is predicted to consist of five consecutive alpha helices (by PSI-PRED), it is sufficiently divergent to warrant being regarded as a separate sub-family (IF).
The gene name comes from the E. coli gene. There is currently no information regarding the function of this gene. |
| References | RN [1]
RM PMID: 7966317
RT Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approac
h to database search.
RA Koonin EV, Tatusov RL.
RL J Mol Biol 1994 Nov 18;244(1):125-32 |
