Accession | TIGR01528 |
Name | NMN_trans_PnuC |
Function | nicotinamide mononucleotide transporter PnuC |
Gene Symbol | pnuC |
Trusted Cutoff | 42.45 |
Domain Trusted Cutoff | 42.45 |
Noise Cutoff | 37.95 |
Domain Noise Cutoff | 37.95 |
Isology Type | subfamily |
HMM Length | 187 |
Mainrole Category | Transport and binding proteins |
Subrole Category | Other |
Gene Ontology Term | GO:0015663: nicotinamide mononucleotide transmembrane transporter activity molecular_function |
| GO:0015890: nicotinamide mononucleotide transport biological_process |
| GO:0016021: integral to membrane cellular_component |
Author | Haft DH |
Entry Date | Jun 3 2002 4:16PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | The PnuC protein of E. coli is membrane protein responsible for nicotinamide mononucleotide transport, subject to regulation by interaction with the NadR (also called NadI) protein (see TIGR01526). This HMM defines a region corresponding to most of the length of PnuC, found primarily in pathogens. The extreme N- and C-terminal regions are poorly conserved and not included in the alignment and model. |
References | RM 1991724
RT Activity of the nicotinamide mononucleotide transport system is regulated in Salmonella typhimurium.
RA Zhu N, Olivera BM, Roth JR.
RL J Bacteriol 1991 Feb;173(3):1311-20 |