HMM Summary Page: TIGR01504
Accession | TIGR01504 |
Name | glyox_carbo_lig |
Function | glyoxylate carboligase |
Gene Symbol | gcl |
Trusted Cutoff | 711.20 |
Domain Trusted Cutoff | 711.20 |
Noise Cutoff | 589.15 |
Domain Noise Cutoff | 589.15 |
Isology Type | equivalog |
EC Number | 4.1.1.47 |
HMM Length | 589 |
Author | Haft DH |
Entry Date | May 10 2002 3:14PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Glyoxylate carboligase, also called tartronate-semialdehyde synthase, releases CO2 while synthesizing a single molecule of tartronate semialdehyde from two molecules of glyoxylate. It is a thiamine pyrophosphate-dependent enzyme, closely related in sequence to the large subunit of acetolactate synthase. In the D-glycerate pathway, part of allantoin degradation in the Enterobacteriaceae, tartronate semialdehyde is converted to D-glycerate and then 3-phosphoglycerate, a product of glycolysis and entry point in the general metabolism. |
References | DR EXPERIMENTAL; SP|P30146; Escherichia coli DR OUTGROUP; SP|P42463; acetolactate synthase large subunit |
Genome Property | GenProp0689: glyoxalate conversion to phosphoglycerate (HMM) |