HMM Summary Page: TIGR01319

AccessionTIGR01319
NameglmL_fam
Functionconserved hypothetical protein
Trusted Cutoff204.05
Domain Trusted Cutoff204.05
Noise Cutoff50.65
Domain Noise Cutoff50.65
Isology Typesubfamily
HMM Length456
AuthorHaft DH
Entry DateAug 6 2001 1:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis small family includes, so far, an uncharacterized protein from E. coli O157:H7 and GlmL from Clostridium tetanomorphum and Clostridium cochlearium. GlmL is located between the genes for the two subunits, epsilon (GlmE) and sigma (GlmS), of the coenzyme-B12-dependent glutamate mutase (methylaspartate mutase), the first enzyme in a pathway of glutamate fermentation. Members shows significant sequence similarity to the hydantoinase branch of the hydantoinase/oxoprolinase family (PF01968).
ReferencesRM 7880251 RT Characterization of the coenzyme-B12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli. RA Zelder O, Beatrix B, Leutbecher U, Buckel W. RL Eur J Biochem 1994 Dec 1;226(2):577-85RM 7880251