HMM Summary Page: TIGR01316

AccessionTIGR01316
NamegltA
Functionglutamate synthase (NADPH), homotetrameric
Gene SymbolgltA
Trusted Cutoff471.75
Domain Trusted Cutoff471.75
Noise Cutoff394.95
Domain Noise Cutoff394.95
Isology Typeequivalog
EC Number1.4.1.13
HMM Length449
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryGlutamate family
Gene Ontology TermGO:0004355: glutamate synthase (NADPH) activity molecular_function
GO:0006537: glutamate biosynthetic process biological_process
AuthorHaft DH
Entry DateJul 31 2001 4:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is homologous to the small subunit of NADPH and NADH forms of glutamate synthase as found in eukaryotes and some bacteria. This protein is found in numerous species having no homolog of the glutamate synthase large subunit. The prototype of the family, from Pyrococcus sp. KOD1, was shown to be active as a homotetramer and to require NADPH.
ReferencesRM 9202379 RT Gene cloning, sequencing and enzymatic properties of glutamate synthase from the hyperthermophilic archaeon Pyrococcus sp. KOD1. RA Jongsareejit B, Rahman RN, Fujiwara S, Imanaka T RL Mol Gen Genet 1997 May;254(6):635-42RM 9202379 DR EXPERIMENTAL; EGAD|130457; Pyrococcus sp. KOD1RM 9202379 RT Gene cloning, sequencing and enzymatic properties of glutamate synthase from the hyperthermophilic archaeon Pyrococcus sp. KOD1. RA Jongsareejit B, Rahman RN, Fujiwara S, Imanaka T RL Mol Gen Genet 1997 May;254(6):635-42RM 9202379 DR EXPERIMENTAL; EGAD|130457; Pyrococcus sp. KOD1