| Accession | TIGR01143 |
| Name | murF |
| Function | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase |
| Gene Symbol | murF |
| Trusted Cutoff | 288.60 |
| Domain Trusted Cutoff | 288.60 |
| Noise Cutoff | 233.90 |
| Domain Noise Cutoff | 233.90 |
| Isology Type | subfamily |
| EC Number | 6.3.2.10 |
| HMM Length | 418 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0009252: peptidoglycan biosynthetic process biological_process |
| | GO:0047480: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity molecular_function |
| Author | Dodson RJ, Haft DH |
| Entry Date | Feb 2 2001 5:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. |
| Genome Property | GenProp0158: peptidoglycan(murein) biosynthesis (HMM) |
