| Accession | TIGR01121 |
| Name | D_amino_aminoT |
| Function | D-amino-acid transaminase |
| Gene Symbol | dat |
| Trusted Cutoff | 277.45 |
| Domain Trusted Cutoff | 277.45 |
| Noise Cutoff | 155.80 |
| Domain Noise Cutoff | 155.80 |
| Isology Type | equivalog |
| EC Number | 2.6.1.21 |
| HMM Length | 276 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Amino acids and amines |
| Gene Ontology Term | GO:0019480: L-alanine oxidation to pyruvate via D-alanine biological_process |
| | GO:0047810: D-alanine:2-oxoglutarate aminotransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jan 12 2001 2:33PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn.
Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. |
| References | RM 89123327
RT Thermostable D-amino acid aminotransferase from a thermophilic Bacillus species. Purification, characterization, and active site sequence determination.
RA Tanizawa K, Masu Y, Asano S, Tanaka H, Soda K
RL J Biol Chem 1989 Feb 15;264(5):2445-9 |
