| Accession | TIGR01055 |
| Name | parE_Gneg |
| Function | DNA topoisomerase IV, B subunit |
| Gene Symbol | parE |
| Trusted Cutoff | 723.35 |
| Domain Trusted Cutoff | 723.35 |
| Noise Cutoff | 680.20 |
| Domain Noise Cutoff | 680.20 |
| Isology Type | equivalog |
| EC Number | 5.99.1.- |
| HMM Length | 625 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0003918: DNA topoisomerase (ATP-hydrolyzing) activity molecular_function |
| | GO:0006265: DNA topological change biological_process |
| | GO:0009340: DNA topoisomerase IV complex cellular_component |
| Author | Haft DH |
| Entry Date | Nov 29 2000 4:43PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason.
This protein is active as an alpha(2)beta(2) heterotetramer. |
