HMM Summary Page: TIGR00977
Accession | TIGR00977 |
Name | citramal_synth |
Function | citramalate synthase |
Gene Symbol | cimA |
Trusted Cutoff | 450.00 |
Domain Trusted Cutoff | 450.00 |
Noise Cutoff | 325.00 |
Domain Noise Cutoff | 325.00 |
Isology Type | equivalog |
EC Number | 2.3.1.182 |
HMM Length | 526 |
Mainrole Category | Unknown function |
Subrole Category | General |
Author | Haft DH |
Entry Date | Sep 29 2000 4:43PM |
Last Modified | Sep 15 2014 12:45PM |
Comment | This model includes GSU1798 and is now known to represent citramalate synthase. Members are related to 2-isopropylmalate synthases and homocitrate synthases but phylogenetically distinct. The role is isoleucine biosynthesis, the first dedicated step. |
References | RN [1] RM PMID:18245290 RT Elucidation of an alternate isoleucine biosynthesis pathway in Geobacter sulfurreducens. RA Risso C, Van Dien SJ, Orloff A, Lovley DR, Coppi MV RL J Bacteriol. 2008 Apr;190(7):2266-74. doi: 10.1128/JB.01841-07. |
Genome Property | GenProp0193: lysine biosynthesis via alpha-aminoadipate (AAA pathway) (HMM) |