Accession | TIGR00834 |
Name | ae |
Function | anion exchange protein |
Trusted Cutoff | 599.45 |
Domain Trusted Cutoff | 599.45 |
Noise Cutoff | 445.45 |
Domain Noise Cutoff | 445.45 |
Isology Type | subfamily |
HMM Length | 900 |
Mainrole Category | Transport and binding proteins |
Subrole Category | Anions |
Author | Paulsen IT, Saier MH, Loftus BJ |
Entry Date | Jul 25 2000 6:19PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | The Anion Exchanger (AE) Family (TC 2.A.31)
Characterized protein members of the AE family are found only in animals.
They preferentially catalyze anion exchange (antiport) reactions, typically acting as HCO3-:Cl- antiporters, but also transporting a range of other inorganic and organic anions. Additionally, renal Na+:HCO3- cotransporters have been found to be members of the AE family. They catalyze the reabsorption of HCO3- in the renal proximal tubule.
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References | A2 hmmalign
SE Ipaulsen
AL clustalw_manual
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