Accession | TIGR00798 |
Name | mtc |
Function | tricarboxylate carrier |
Trusted Cutoff | 322.80 |
Domain Trusted Cutoff | 322.80 |
Noise Cutoff | 225.45 |
Domain Noise Cutoff | 225.45 |
Isology Type | subfamily |
HMM Length | 317 |
Mainrole Category | Transport and binding proteins |
Subrole Category | Carbohydrates, organic alcohols, and acids |
Author | Paulsen IT, Saier MH, Loftus BJ |
Entry Date | Jul 7 2000 1:40PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | The MTC family consists of a limited number of homologues, all from eukaryotes. A single member of the family has been functionally characterized, the tricarboxylate carrier from rat liver mitochondria. The rat liver mitochondrial tricarboxylate carrier has been reported to transport citrate, cis-aconitate, threo-D-isocitrate, D- and L-tartrate, malate, succinate and phosphoenolpyruvate. It presumably functions by a proton symport mechanism. |
References | SE Ipaulsen
DR URL; http://www-biology.ucsd.edu/~msaier/transport/2_A_54.html
DR Interpro; IPR001993
DR PFAM; PF00153 |