| Accession | TIGR00765 |
| Name | yihY_not_rbn |
| Function | YihY family inner membrane protein |
| Gene Symbol | yihY |
| Trusted Cutoff | 73.15 |
| Domain Trusted Cutoff | 73.15 |
| Noise Cutoff | 43.25 |
| Domain Noise Cutoff | 43.25 |
| Isology Type | subfamily_domain |
| HMM Length | 259 |
| Mainrole Category | Unknown function |
| Subrole Category | General |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0005575: cellular_component cellular_component |
| | GO:0008150: biological_process biological_process |
| Author | Haft DH |
| Entry Date | Jun 13 2000 5:57PM |
| Last Modified | Dec 8 2011 11:33AM |
| Comment | Initial identification of members of this protein family was based on characterization of the yihY gene product as ribonuclease BN in Escherichia coli. This identification has been withdrawn, as the group now finds the homolog in E. coli of RNase Z is the true ribonuclease BN rather than a strict functional equivalent of RNase Z.
Members of this subfamily include the largely uncharacterized BrkB (Bordetella resist killing by serum B) from Bordetella pertussis. Some members have an additional C-terminal domain. Paralogs from E. coli (yhjD) and Mycobactrium tuberculosis (Rv3335c) are part of a smaller, related subfamily that form their own cluster. |
| References | DR EXPERIMENTAL; EGAD:17695; Escherichia coli
DR OUTGROUP; EGAD|10508|EC3522; Escherichia coli
DR OUTGROUP; EGAD|160884|Rv3335c; Mycobacterium tuberculosis
RN [1]
RM 15764599
RT The RNase Z homologue encoded by Escherichia coli elaC gene is RNase BN.
RA Ezraty B, Dahlgren B, Deutscher MP.
RL J Biol Chem. 2005 Apr 29;280(17):16542-5.
RN [2]
RM 20092870
RT Purification and characterization of the tRNA-processing enzyme RNase BN.
RA Callahan C, Neri-Cortes D, Deutscher MP
RL J Biol Chem 2000 Jan 14;275(2):1030-4
RN [3]
RM 93015723
RT The presence of only one of five exoribonucleases is sufficient to support the growth of Escherichia coli.
RA Kelly KO, Deutscher MP
RL J Bacteriol 1992 Oct;174(20):6682-4
DR HAMAP; MF_00672; 73 of 74 |
