| Accession | TIGR00761 |
| Name | argB |
| Function | acetylglutamate kinase |
| Gene Symbol | argB |
| Trusted Cutoff | 151.30 |
| Domain Trusted Cutoff | 151.30 |
| Noise Cutoff | 113.20 |
| Domain Noise Cutoff | 113.20 |
| Isology Type | equivalog_domain |
| EC Number | 2.7.2.8 |
| HMM Length | 231 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Glutamate family |
| Gene Ontology Term | GO:0003991: acetylglutamate kinase activity molecular_function |
| | GO:0006592: ornithine biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Jun 13 2000 5:57PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes N-acetylglutamate kinases (ArgB) of many prokaryotes and the N-acetylglutamate kinase domains of multifunctional proteins from yeasts. This enzyme is the second step in the "acetylated" ornithine biosynthesis pathway. A related group of enzymes representing the first step of the pathway contain a homologous domain and are excluded from this model. |
| References | AL clustalw_manual
DR EXPERIMENTAL; EGAD|15079|15117; Bacillus stearothermophilus
DR EXPERIMENTAL; EGAD|8342|EC3959; Escherichia coli
DR EXPERIMENTAL; EGAD|52213|YER069W; Saccharomyces cerevisiae
DR OUTGROUP; EGAD|10737|EC2818; N-acetylglutamate synthetase; Escherichia coli
RN [1]
RM 91301142
RT Determination of amino acid sequences involved in the processing of the ARG5/ARG6 precursor in Saccharomyces cerevisiae.
RA Boonchird C, Messenguy F, Dubois E
RL Eur J Biochem 1991 Jul 15;199(2):325-35
DR HAMAP; MF_00082; 441 of 446 |
| Genome Property | GenProp0118: ornithine biosynthesis from glutamate, acetylated branch (HMM) |
| | GenProp0193: lysine biosynthesis via alpha-aminoadipate (AAA pathway) (HMM) |
