Accession | TIGR00684 |
Name | narJ |
Function | nitrate reductase molybdenum cofactor assembly chaperone |
Gene Symbol | narJ |
Trusted Cutoff | 59.35 |
Domain Trusted Cutoff | 59.35 |
Noise Cutoff | 48.55 |
Domain Noise Cutoff | 48.55 |
Isology Type | equivalog |
HMM Length | 152 |
Mainrole Category | Protein fate |
Subrole Category | Protein folding and stabilization |
Gene Ontology Term | GO:0051082: unfolded protein binding molecular_function |
| GO:0051131: chaperone-mediated protein complex assembly biological_process |
Author | Haft DH, Loftus BJ |
Entry Date | Jan 13 2000 2:40PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This protein is termed NarJ in most species that have a single copy, and has been called the delta subunit of nitrate reductase. However, although it is required for correct assembly of active enzyme, it dissociates and is not part of the enzyme. Two hits to this HMM are found each in E. coli and in Mycobacterium tuberculosis, but in each case duplication to create paralogs appears to be recent. The NarX protein of Mycobacterium tuberculosis includes one of these paralogs as a domain, fused to structural domains of nitrate reductases before and after the NarJ-homologous region. |
References | RM 98294038
RT NarJ is a specific chaperone required for molybdenum cofactor assembly in nitrate reductase A of Escherichia coli.
RA Blasco F, Dos Santos JP, Magalon A, Frixon C, Guigliarelli B, Santini CL, Giordano G
RL Mol Microbiol 1998 May;28(3):435-47 |
Genome Property | GenProp0636: respiratory nitrate reductase (HMM) |