| Accession | TIGR00587 |
| Name | nfo |
| Function | apurinic endonuclease (APN1) |
| Trusted Cutoff | 129.65 |
| Domain Trusted Cutoff | 129.65 |
| Noise Cutoff | 112.50 |
| Domain Noise Cutoff | 112.50 |
| Isology Type | subfamily |
| HMM Length | 279 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0003906: DNA-(apurinic or apyrimidinic site) lyase activity molecular_function |
| | GO:0006281: DNA repair biological_process |
| Author | Loftus BJ, Eisen JA |
| Entry Date | Oct 19 1999 6:19PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | All proteins in this family for which functions are known are 5' AP endonculeases that are used in base excision repair and the repair of abasic sites in DNA.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
|
| References | GA hmmsearch
GA hmmsearch
GA hmmsearch
DR EGAD; 54020;
DR SWISSPROT; P22936;
DR HAMAP; MF_00152; 167 of 170 |
