Accession | TIGR00578 |
Name | ku70 |
Function | ATP-dependent DNA helicase II, 70 kDa subunit (ku70) |
Trusted Cutoff | 194.25 |
Domain Trusted Cutoff | 194.25 |
Noise Cutoff | 154.65 |
Domain Noise Cutoff | 154.65 |
Isology Type | superfamily |
HMM Length | 586 |
Mainrole Category | DNA metabolism |
Subrole Category | DNA replication, recombination, and repair |
Author | Loftus BJ, Eisen JA |
Entry Date | Oct 19 1999 6:19PM |
Last Modified | Feb 28 2011 3:55PM |
Comment | Proteins in this family are involved in non-homologous end joining, a process used for the repair of double stranded DNA breaks. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). Cutoff does not detect the putative ku70 homologs in yeast. |
References | A2 hmmalign
GA hmmsearch
DR SWISSPROT; P12956;
RM 89174787; |