| Accession | TIGR00562 |
| Name | proto_IX_ox |
| Function | protoporphyrinogen oxidase |
| Gene Symbol | hemG |
| Trusted Cutoff | 97.85 |
| Domain Trusted Cutoff | 97.85 |
| Noise Cutoff | 73.05 |
| Domain Noise Cutoff | 73.05 |
| Isology Type | equivalog |
| EC Number | 1.3.3.4 |
| HMM Length | 470 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Heme, porphyrin, and cobalamin |
| Gene Ontology Term | GO:0004729: oxygen-dependent protoporphyrinogen oxidase activity molecular_function |
| | GO:0006779: porphyrin-containing compound biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Oct 19 1999 4:31PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear.
This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. |
| References | A2 hmmalign
AL ClustalW
RN [1]
RM 96224138
RN [2]
RM 95229621
RN [3]
RM 99003470 |
| Genome Property | GenProp0221: protoporphyrin IX biosynthesis from uroporphyrinogen III (HMM) |
