Accession | TIGR00561 |
Name | pntA |
Function | NAD(P)(+) transhydrogenase (AB-specific), alpha subunit |
Gene Symbol | pntA |
Trusted Cutoff | 444.40 |
Domain Trusted Cutoff | 444.40 |
Noise Cutoff | 258.60 |
Domain Noise Cutoff | 258.60 |
Isology Type | equivalog |
EC Number | 1.6.1.2 |
HMM Length | 511 |
Mainrole Category | Energy metabolism |
Subrole Category | Electron transport |
Gene Ontology Term | GO:0008750: NAD(P)+ transhydrogenase (AB-specific) activity molecular_function |
| GO:0055114: oxidation-reduction process biological_process |
Author | Haft DH |
Entry Date | Oct 19 1999 4:31PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This integral membrane protein is the alpha subunit of alpha 2 beta 2 tetramer that couples the proton transport across the membrane to the reversible transfer of hydride ion equivalents between NAD and NADP. An alternate name is pyridine nucleotide transhydrogenase alpha subunit. The N-terminal region is homologous to alanine dehydrogenase.
In some species, such as Rhodospirillum rubrum, the alpha chain is replaced by two shorter chains, both with some homology to the full-length alpha chain modeled here. These score below the trusted cutoff. |
References | A2 hmmalign
DR ECOCYC; EG10744; pntA
RM 98358599
RT Site-directed mutagenesis of the proton-pumping pyridine nucleotide transhydrogenase of Escherichia coli.
RA Bragg PD
RL Biochim Biophys Acta 1998 Jun 10;1365(1-2):98-104
AL clustalw |