| Accession | TIGR00535 |
| Name | SAM_DCase |
| Function | S-adenosylmethionine decarboxylase proenzyme |
| Trusted Cutoff | 233.15 |
| Domain Trusted Cutoff | 233.15 |
| Noise Cutoff | 127.30 |
| Domain Noise Cutoff | 127.30 |
| Isology Type | equivalog |
| EC Number | 4.1.1.50 |
| HMM Length | 334 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Polyamine biosynthesis |
| Gene Ontology Term | GO:0004014: adenosylmethionine decarboxylase activity molecular_function |
| | GO:0006597: spermine biosynthetic process biological_process |
| | GO:0008295: spermidine biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Oct 19 1999 4:29PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme is a key regulatory enzyme of the polyamine synthetic pathway.
This protein is a pyruvoyl-dependent enzyme. The proenzyme is cleaved at a Ser residue that becomes a pyruvoyl group active site. |
| References | A2 hmmalign
AL ClustalW
DR PROSITE; PDOC01038; S-adenosylmethionine decarboxylase signature; |
