| Accession | TIGR00479 |
| Name | rumA |
| Function | 23S rRNA (uracil-5-)-methyltransferase RumA |
| Gene Symbol | rumA |
| Trusted Cutoff | 183.55 |
| Domain Trusted Cutoff | 183.55 |
| Noise Cutoff | 159.95 |
| Domain Noise Cutoff | 159.95 |
| Isology Type | equivalog |
| EC Number | 2.1.1.- |
| HMM Length | 432 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0000154: rRNA modification biological_process |
| | GO:0008649: rRNA methyltransferase activity molecular_function |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. |
| References | RM 11779873
RT Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.
RA Agarwalla S, Kealey JT, Santi DV, Stroud RM.
RL J Biol Chem. 2002 Mar 15;277(11):8835-40.
DR SWISSPROT; P55135; Escherichia coli
DR PROSITE; PDOC00945;
DR ECOCYC; EG11247;
DR HAMAP; MF_01010; 104 of 105 |
