| Accession | TIGR00419 |
| Name | tim |
| Function | triose-phosphate isomerase |
| Gene Symbol | tpiA |
| Trusted Cutoff | 130.60 |
| Domain Trusted Cutoff | 130.60 |
| Noise Cutoff | 113.50 |
| Domain Noise Cutoff | 113.50 |
| Isology Type | equivalog |
| EC Number | 5.3.1.1 |
| HMM Length | 228 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Glycolysis/gluconeogenesis |
| Gene Ontology Term | GO:0004807: triose-phosphate isomerase activity molecular_function |
| | GO:0006096: glycolysis biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. |
| References | DR ECOCYC; EG11015;
DR PROSITE; PDOC00155;
SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00147; 450 of 469 |
| Genome Property | GenProp0120: pentose phosphate cycle (HMM) |
| | GenProp0691: glycolysis (HMM) |
