HMM Summary Page: TIGR00365

AccessionTIGR00365
NameTIGR00365
Functionmonothiol glutaredoxin, Grx4 family
Gene SymbolgrxD
Trusted Cutoff117.10
Domain Trusted Cutoff117.10
Noise Cutoff85.70
Domain Noise Cutoff85.70
Isology Typeequivalog
HMM Length99
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
Gene Ontology TermGO:0009055: electron carrier activity molecular_function
GO:0030508: thiol-disulfide exchange intermediate activity molecular_function
AuthorHaft DH, Loftus BJ
Entry DateApr 20 1999 2:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe gene for the member of this glutaredoxin family in E. coli, originally designated ydhD, is now designated grxD. Its protein, Grx4, is a monothiol glutaredoxin similar to Grx5 of yeast, which is involved in iron-sulfur cluster formation.
ReferencesRN [1] RM PMID:15833738 RT A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase. RA Fernandes AP, Fladvad M, Berndt C, Andresen C, Lillig CH, Neubauer P, Sunnerhagen M, Holmgren A, Vlamis-Gardikas A RL J Biol Chem. 2005 Jul 1;280(26):24544-52.