| Accession | TIGR00223 |
| Name | panD |
| Function | aspartate 1-decarboxylase |
| Gene Symbol | panD |
| Trusted Cutoff | 106.00 |
| Domain Trusted Cutoff | 106.00 |
| Noise Cutoff | 83.70 |
| Domain Noise Cutoff | 83.70 |
| Isology Type | equivalog |
| EC Number | 4.1.1.11 |
| HMM Length | 126 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Pantothenate and coenzyme A |
| Gene Ontology Term | GO:0004068: aspartate 1-decarboxylase activity molecular_function |
| | GO:0015940: pantothenate biosynthetic process biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are aspartate 1-decarboxylase, the enzyme that makes beta-alanine and C02 from aspartate. Beta-alanine is then used to make the vitamin pantothenate, from which coenzyme A is made. Aspartate 1-decarboxylase is synthesized as a proenzyme, then cleaved to an alpha (C-terminal) and beta (N-terminal) subunit with a pyruvoyl group. |
| References | SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00446; 266 of 276 |
| Genome Property | GenProp0124: pantothenate biosynthesis from aspartate and 2-oxoisovalerate (HMM) |
