| Accession | TIGR00218 |
| Name | manA |
| Function | mannose-6-phosphate isomerase, class I |
| Gene Symbol | manA |
| Trusted Cutoff | 116.20 |
| Domain Trusted Cutoff | 116.20 |
| Noise Cutoff | 59.15 |
| Domain Noise Cutoff | 59.15 |
| Isology Type | equivalog |
| EC Number | 5.3.1.8 |
| HMM Length | 359 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Sugars |
| Gene Ontology Term | GO:0004476: mannose-6-phosphate isomerase activity molecular_function |
| | GO:0005975: carbohydrate metabolic process biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The names phosphomannose isomerase and mannose-6-phosphate isomerase are synonomous. This family contains two rather deeply branched groups. One group contains an experimentally determined phosphomannose isomerase of Streptococcus mutans as well as three uncharacterized paralogous proteins of Bacillus subtilis, all at more than 50 % identity to each other, plus a more distant homolog from Archaeoglobus fulgidus. The other group contains members from E. coli, budding yeast, Borrelia burgdorferi, etc. |
| References | A2 hmmalign
SE TIGR
GA hmmls
AL clustalw, belvu
BD 0269
DR PROSITE; PDOC00746;
DR PFAM; PF01238; PMI_typeI |
