| Accession | TIGR00131 |
| Name | gal_kin |
| Function | galactokinase |
| Gene Symbol | galK |
| Trusted Cutoff | 226.65 |
| Domain Trusted Cutoff | 226.65 |
| Noise Cutoff | 185.00 |
| Domain Noise Cutoff | 185.00 |
| Isology Type | equivalog |
| EC Number | 2.7.1.6 |
| HMM Length | 388 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Sugars |
| Gene Ontology Term | GO:0004335: galactokinase activity molecular_function |
| | GO:0006012: galactose metabolic process biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.
The galactokinases found by this HMM are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity.
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| References | DR PROSITE; PDOC0054;
SE TIGR
GA hmmls
AL clustalw, belvu, seaview
DR HAMAP; MF_00246; 85 of 86 |
| Genome Property | GenProp0143: Leloir pathway (galactose/glucose interconversion) (HMM) |
