HMM Summary Page: TIGR00005
| Accession | TIGR00005 |
| Name | rluA_subfam |
| Function | pseudouridine synthase, RluA family |
| Trusted Cutoff | 192.70 |
| Domain Trusted Cutoff | 192.70 |
| Noise Cutoff | 136.20 |
| Domain Noise Cutoff | 136.20 |
| Isology Type | subfamily |
| EC Number | 5.4.99.- |
| HMM Length | 298 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0001522: pseudouridine synthesis biological_process |
| GO:0009451: RNA modification biological_process | |
| GO:0009982: pseudouridine synthase activity molecular_function | |
| Author | Dodson RJ, Richardson DL |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | In E. coli, RluD (SfhB) modifies uridine to pseudouridine at 23S RNA U1911, 1915, and 1917, RluC modifies 955, 2504 and 2580, and RluA modifies U746 and tRNA U32. An additional homolog from E. coli outside this family, TruC (SP|Q46918), modifies uracil-65 in transfer RNAs to pseudouridine. |
| References | SE TIGR A2 hmmalign |