Description | Aah and TibC are protein O-heptosyltransferases that glycosylate certain repeat-rich proteins at multiple sites. Their targets are the autotransporter (T5SS) proteins AIDA (autotransporter adhesin involved in diffuse adherence) and TibA, respectively. Similar tandem gene pairs occur in Burkholderia vietnamiensis G4, Granulibacter bethesdensis CGDNIH1, Cronobacter sakazakii ATCC BAA-894, and Bradyrhizobium sp. ORS278. In Burkholderia mallei, the heptosyltransferase occurs next to BimA, an autotransporter virulence factor involved in actin-based motility, suggesting glycosylation, although BimA lacks the repeat structure recognized by model TIGR04415. |