Accession | GenProp0962 |
Name | methanobactin biosynthesis, Mb-OB3b family |
Type | SYSTEM |
Description | Methanobactins are siderophore-like copper chelators. The charter member for this Genome Property is Methylosinus trichosporium OB3b, in which the methanobactin is made from a 30-residue ribosomally translated precursor. The only other system known so far is in Azospirillum sp. B510. Protein families TIGR04039, TIGR04052, and TIGR04061 contain proteins in which the Methylosinus and Azospirillum are mutually the best hits among all genomes, suggesting they act in the methanobactin system. |
Parent Property | GenProp0077: natural products biosynthesis
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Literature References | [ 1 ]Krentz BD, Mulheron HJ, Semrau JD, Dispirito AA, Bandow NL, Haft DH, Vuilleumier S, Murrell JC, McEllistrem MT, Hartsel SC, Gallagher WH A comparison of methanobactins from Methylosinus trichosporium OB3b and Methylocystis strain Sb2 predicts methanobactins are synthesized from diverse peptide precursors modified to create a common core for binding and reducing copper ions. Biochemistry. 2010 Nov 30;49(47):10117-30. PMID 20961038 |
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Gene Ontology Term | GO:0015677: copper ion import (biological_process)
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Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
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methanobactin precursor, Mb-OB3b family | mbnA | YES | TIGR04071 (HMM): methanobactin precursor, Mb-OB3b family | GO:0015677: copper ion import
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methanobactin biosynthesis cassette protein MbnB | mbnB | YES | TIGR04159 (HMM): methanobactin biosynthesis cassette protein MbnB | GO:0015677: copper ion import
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methanobactin biosynthesis cassette protein MbnC | mbnC | YES | TIGR04160 (HMM): methanobactin biosynthesis cassette protein MbnC | GO:0015677: copper ion import
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Accession | Name |
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GenProp0014 | polyketide biosynthesis, type I |
GenProp0015 | polyketide biosynthesis, type II |
GenProp0040 | thiotemplate type non-ribosomal peptide biosynthesis |
GenProp0169 | hybrid NRPS-PKS natural pruduct biosynthesis genes |
GenProp0724 | phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate |
GenProp0757 | quorum-sensing, autoinducer-2 system |
GenProp0758 | lycopene biosynthesis from IPP |
GenProp0770 | siderophore biosynthesis |
GenProp0807 | bacteriocin system, heterocycle biosynthesis group |
GenProp0808 | bacteriocin system, TIGR01847 leader group |
GenProp0809 | bacteriocin system, lactococcin 972 group |
GenProp0823 | violacein biosynthesis |
GenProp0825 | bacteriocin system, circular bacteriocin group |
GenProp0853 | lantibiotic system, gallidermin/epidermin family |
GenProp0861 | bacteriocin system, NHLP (nif11/nitrile hydratase leader peptide) transport group |
GenProp0901 | post-ribosomal natural product synthesis system, Burkholderia TOMM-type |
GenProp0919 | SCIFF/radical SAM Clostridial gene pair |
GenProp0920 | radical SAM Y_X(10)_GDL system |
GenProp0921 | radical SAM pair and His-Xaa-Ser repeats peptide |
GenProp0936 | bacteriocin system, sporulation delay protein group |
GenProp0945 | radical SAM maturase bacteriocin system, CLI_3235 type |
GenProp0954 | radical SAM-cylized peptide, Pep1357C family |
GenProp0955 | modified peptide/radical SAM maturase system, YydFG family |
GenProp0956 | radical SAM maturase/selenobacteriocin system |
GenProp0967 | radical SAM maturase system, CXXX repeats type |
GenProp0982 | radical SAM maturase system, FibroRumin system |
GenProp0984 | radical SAM maturase system, GG-Bacteroidales group |
GenProp0990 | cobaltopeptin biosynthesis |
GenProp0991 | ATP-grasp maturase system, microviridin/marinostatin class |
GenProp1000 | ATP-grasp maturase system, uncharacterized |
GenProp1002 | grasp-with-spasm peptide maturase system |
GenProp1003 | cysteine S-glycopeptide biosynthesis, sublancin family |
GenProp1029 | radical SAM/SPASM system SynChlorMet |
GenProp1037 | radical SAM/SPASM system GRRM |
GenProp1052 | geopeptide radical SAM/SPASM maturase system |
GenProp1062 | radical SAM/SPASM system Clo7bot |
GenProp1065 | radical SAM/SPASM TIGR04347/TIGR04031 system |
GenProp1078 | sporulation killing factor system |
GenProp1083 | cyanobactin-like ribosomal natural product biosynthesis |
GenProp1084 | enduracididine biosynthesis |
GenProp1090 | radical SAM/SPASM maturase system XYE |
GenProp1097 | bacimethrin biosynthesis |
GenProp1098 | 3-methylarginine biosynthesis |