| Accession | GenProp0949 |
| Name | O111(Ec) antigen biosynthesis |
| Type | METAPATH |
| Description | The O111 O-antigen is observed in E. coli strain 11128. The structure of the O111 antigen is a branched pentasaccharide containing two colitose sugars [1]. The O111 biosynthetic cluster encodes three sugar transferases WbdHLM, the wzx and wzy components as well as the enzymes for the biosynthesis of GDP-L-colitose from D-fructose-6P via GDP-mannose. One of the transferases, WbdM, is responsible for attaching both colitose residues at both the 3 and 6 positions of alpha-D-glucose as the last steps of the monomer synthesis. |
| Parent Property | GenProp0913: E. coli O-antigen monomer biosynthesis clusters
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| Literature References | [ 1 ]Stevenson G, Dieckelmann M, Reeves PR Determination of glycosyltransferase specificities for the Escherichia coli O111 O antigen by a generic approach. Appl Environ Microbiol. 2008 Feb;74(4):1294-8. Epub 2007 Dec 21. PMID 18156323
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| Web References | ECODAB: O111
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