Genome Property Definition Page
Accession | GenProp0943 | |
Name | pyruvate formate-lyase system | |
Type | SYSTEM | |
Description | This property consists of the glycine radical enzyme, pyruvate-formate lyase (EC 2.3.1.54, also called formate C-acetyltransferase) and its activating enzyme, [Formate-C-acetyltransferase]-activating enzyme (EC 1.97.1.4). In most Proteobacteria, the gene pair is accompanied by the formate channel gene focA. FocA forms a pentameric channel that can pass formate but not water, and that belongs to the same transporter family as nitrate transporter NirC. | |
Parent Property | GenProp0075: protein modification, prosthetic groups and cofactors | |
Literature References |
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Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
pyruvate formate-lyase | PFL | YES | TIGR01774 (HMM): glycyl radical enzyme, PFL2/glycerol dehydratase family TIGR01255 (HMM): formate acetyltransferase | |
pyruvate formate-lyase activating enzyme | PFLA | YES | TIGR02493 (HMM): pyruvate formate-lyase 1-activating enzyme | |
formate transporter | PF_FocA | NO | PF01226 (HMM-CLUST): formate/nitrite transporter | |
autonomous glycyl radical cofactor | spare | NO | TIGR04365 (HMM): autonomous glycyl radical cofactor GrcA |
Parent Properties
Accession | Name |
---|---|
GenProp0075 | protein modification, prosthetic groups and cofactors |
Sibling Properties
Accession | Name |
---|---|
GenProp0002 | coenzyme F420 utilization |
GenProp0016 | selenocysteine system |
GenProp0061 | lipoprotein system lgt/lsp/lnt |
GenProp0127 | Tat (Sec-independent) protein export |
GenProp0284 | cobalamin-utilizing enzymes |
GenProp0295 | prokaryotic N-terminal cleavage/methylation, type IV pilin-like |
GenProp0726 | selenium-dependent molybdenum hydroxylase system |
GenProp0745 | lipoyl-protein attachment |
GenProp0860 | tryptophan tryptophylquinone modification of methylamine dehydrogenase |
GenProp0918 | anaerobic sulfatase/maturase system |
GenProp0923 | mycothiol system |
GenProp0933 | bacillithiol utilization |
GenProp0938 | glycine radical enzyme system, YjjI/YjjW pair |