Genome Property Definition Page
Accession | GenProp0862 |
Name | pyridoxal phosphate biosynthesis, PdxA/PdxJ pathway |
Type | PATHWAY |
Description | This genome property represents pyridoxal 5-prime phosphate biosynthesis as it occurs in Escherichia coli, from deoxyxylulose 5-phosphate and 4-phosphohydroxy-L-threonine. The key proteins are PdxA and PdxJ. This pathway contrasts with the Pdx1 and Pdx2 pathway, as found in Bacillus subtilis. The current version of this Genome Property assesses only the two signature enzymes PdxA and PdxJ. |
JCVI Role | Pantothenate and coenzyme A |
Parent Property | GenProp0184: cofactor biosynthesis |
Gene Ontology Term | GO:0042823: pyridoxal phosphate biosynthetic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
4-hydroxythreonine-4-phosphate dehydrogenase | pdxA | YES | TIGR00557 (HMM): 4-hydroxythreonine-4-phosphate dehydrogenase PdxA | GO:0042823: pyridoxal phosphate biosynthetic process |
erythronate-4-phosphate dehydrogenase | pdxB | NO | ||
pyridoxal phosphate synthase | pdxJ | YES | TIGR00559 (HMM): pyridoxine 5'-phosphate synthase | GO:0042823: pyridoxal phosphate biosynthetic process |
Parent Properties
Accession | Name |
---|---|
GenProp0184 | cofactor biosynthesis |
Sibling Properties
Accession | Name |
---|---|
GenProp0001 | chorismate biosynthesis via shikimate |
GenProp0030 | glutathione biosynthesis |
GenProp0036 | biotin biosynthesis |
GenProp0038 | tetrahydrofolate biosynthesis from GTP and PABA |
GenProp0057 | NAD(P) biosynthesis from L-aspartate and DHAP |
GenProp0112 | riboflavin, FAD and FMN from GTP and ribulose-5-P |
GenProp0124 | pantothenate biosynthesis from aspartate and 2-oxoisovalerate |
GenProp0136 | ubiquinone biosynthesis from chorismate, aerobic |
GenProp0140 | iron-sulfur cluster assembly systems |
GenProp0170 | coenzyme PQQ biosynthesis |
GenProp0171 | coenzyme A biosynthesis from pantothenate |
GenProp0194 | siroheme biosynthesis from uroporphrinogen-III |
GenProp0220 | uroporhyrinogen III biosynthesis from 5-aminolevulinate |
GenProp0221 | protoporphyrin IX biosynthesis from uroporphyrinogen III |
GenProp0222 | protoheme from protoporphyrin IX |
GenProp0250 | thiamine: hydroxyethylthiazole from 1-deoxy-D-xylulose-5-phosphate, cysteine, either Tyr or Gly |
GenProp0255 | 5-aminolevulinate biosynthesis |
GenProp0261 | thiamin pyrophosphate (TPP) de novo biosynthesis |
GenProp0274 | coenzyme B12 biosynthesis - overview |
GenProp0300 | photosynthetic cofactor biosynthesis |
GenProp0466 | molybdopterin biosynthesis |
GenProp0752 | ergothioneine biosynthesis |
GenProp0753 | mycothiol biosynthesis |
GenProp0759 | para-aminobenzoic acid (PABA) biosynthesis from chorismate |
GenProp0791 | coenzyme F420 biosynthesis |
GenProp0792 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis |
GenProp0836 | menaquinone biosynthesis |
GenProp0860 | tryptophan tryptophylquinone modification of methylamine dehydrogenase |
GenProp0863 | pyridoxal phosphate biosynthesis, Pdx1/Pdx2 pathway |
GenProp0891 | coenzyme M biosynthesis |
GenProp0917 | mycofactocin system |
GenProp0927 | bacillithiol biosynthesis |
GenProp1064 | ovothiol biosynthesis |
GenProp1096 | coenzyme B biosynthesis |