Accession | GenProp0835 |
Name | ATP-dependent protease HslVU |
Type | SYSTEM |
Description | HslVU, also known as ClpQY, is an ATP-dependent protease that resembles proteasomes. The ATPase HslU acts in protein unfolding, while the threonine-type endopeptidase HslV is homologous to the proteasome beta subunit and acts in protein degradation. Members of this family frequently are described as heat shock proteins. |
JCVI Role | Degradation of proteins, peptides, and glycopeptides |
Parent Property | GenProp0301: protein degradation
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Literature References | [ 1 ] Seol JH, Yoo SJ, Shin DH, Shim YK, Kang MS, Goldberg AL, Chung CH The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase. Eur J Biochem. 1997 Aug 1;247(3):1143-50. PMID 9288941 |
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Gene Ontology Term | GO:0006510: ATP-dependent proteolysis (biological_process)
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