Genome Property Definition Page
| Accession | GenProp0698 |
| Name | xanthine catabolism to urate |
| Type | METAPATH |
| Description | The committed step in the catabolism of purines is the oxidation of the purine ring of xanthine (via hypoxanthine) to urate (uric acid). The xanthine may result from the deamination of guanine (or hypoxanthine from adenine), or may be imported via a permease. Several systems exist for the conversion of xanthine to urate including the XdhABC xanthine dehydrogenase complex (GenProp0640), xanthine oxidase and other less well-described oxidoreductases. |
| Parent Property | GenProp0700: purine catabolism via urate, xanthine and allantoin |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| xanthine conversion to urate (uric acid) | X->U | YES | GenProp0640 (GENPROP): xanthine dehydrogenase | |
| source of xanthine | Xan-in | YES | TIGR03173 (HMM): xanthine permease TIGR01178 (HMM): adenine deaminase TIGR02967 (HMM): guanine deaminase |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0700 | purine catabolism via urate, xanthine and allantoin |