Genome Property Definition Page

Accession

GenProp0627

Name

gene pair involved in iron and oxygen metabolism

Type

SYSTEM

Description

The knockout of SO1377 in Shewanella oneidensis results in oxidative damage related to changes in iron metabolism [1]. The adjacent gene, SO1366 is phylogenomically linked and part of an apparent operon.

JCVI Role

Role category not yet assigned

Parent Property

GenProp0475: Unknown biological process
GenProp0820: iron metabolism

Literature References

[ 1 ]Gao W, Liu Y, Giometti CS, Tollaksen SL, Khare T, Wu L, Klingeman DM, Fields MW, Zhou J Knock-out of SO1377 gene, which encodes the member of a conserved hypothetical bacterial protein family COG2268, results in alteration of iron metabolism, increased spontaneous mutation and hydrogen peroxide sensitivity in Shewanella oneidensis MR-1. BMC Genomics. 2006 Apr 6;7(1):76. PMID 16600046

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
SO1376 gene family	SO1376	YES
SO1377 gene family: part of COG2268	SO1377	YES

Parent Properties

Accession	Name
GenProp0475	Unknown biological process
GenProp0820	iron metabolism

Sibling Properties

Accession	Name
GenProp0470	sporadically distributed four-gene operon
GenProp0471	uncharacterized gene pair TIGR02683/TIGR02684
GenProp0472	uncharacterized gene pair TIGR02687/TIGR02688
GenProp0665	peptide chain release operon, RctB-like/PrfH
GenProp0751	Acidobacterial ADOP/PadR gene pairs
GenProp0790	sporadic pair TIGR03545/TIGR03546
GenProp0798	Enterococcus/Aeromonas extended locus
GenProp0830	integral membrane mystery pair
GenProp0854	ParB-rel/ThiF-rel cassette PRTRC
GenProp0868	uncharacterized protein pair with twin-arg and repeat
GenProp0894	Actinobacterial uncharacterized trio
GenProp0916	radical SAM/uncharacterized protein TIGR03936 system
GenProp0940	metallo-mystery pair
GenProp0959	radical SAM/uncharacterized protein TIGR04002 system
GenProp0965	YedE/YedF selenium handling system
GenProp1063	Memo/AMMECR1/rSAM family trio system
GenProp1066	uncharacterized cassette GAK (Grasp, Amphipathic, Kinase)
GenProp1086	Firmicutes/Treponema mobile radical SAM system
GenProp0140	iron-sulfur cluster assembly systems
GenProp0194	siroheme biosynthesis from uroporphrinogen-III
GenProp0222	protoheme from protoporphyrin IX
GenProp0770	siderophore biosynthesis
GenProp0774	ferric citrate transport system
GenProp0828	heme uptake system, NEAT-domain mediated
GenProp0961	heme metabolism pair HutWX