| Accession | GenProp0320 |
| Name | CRISPR system, I-B subtype, Hmari branch |
| Type | SYSTEM |
| Description | CRISPR repeats are by definition Clustered Regularly Interspaced Short Palindromic Repeats, described by Jansen [1]. Certain proteins, including Cas1 to Cas4, are found only in genomes with CRISPR repeats, and are near these repeats. Jansen, et al. describe CRISPR loci as having direct repeats, varying in size from 21 to 37 bp, interspaced by similarly sized non-repetitive sequences. Variants of CRISP/Cas loci (subtypes) have been described (Haft, Selengut, et al., submitted) in which certain groups of subtype-specific genes are found in addition to characteristic sets of the more widely distributed cas genes. The Hmari subtype, so named because this subtype is the only one found in the genome of Haloarcula marismortui ATCC 43049, consists of cas1-6 and the subtype specific genes csh1-2. The repeats associated with this subtype tend to have a periodicity of 66 nucleotides. This subtype is found both in Archaea and Bacteria. |
| JCVI Role | Other |
| Parent Property | GenProp0021: CRISPR region
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| Literature References | [ 1 ]Haft DH, Selengut J, Mo ngodin EF, Nelson KE A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. PLoS Comput Biol. 2005 Nov;1(6):e60. PMID 16292354
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| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|
| Cas1, Hmari region | Cas1 | YES | TIGR00287 (HMM-CLUST): CRISPR-associated endonuclease Cas1 | |
| Cas2, Hmari region | Cas2 | YES | TIGR01573 (HMM-CLUST): CRISPR-associated endonuclease Cas2 | |
| Cas3, Hmari region | Cas3 | YES | TIGR01587 (HMM-CLUST): CRISPR-associated helicase Cas3 | |
| Cas4, Hmari region | Cas4 | YES | TIGR00372 (HMM-CLUST): CRISPR-associated protein Cas4 | |
| Cas5, Hmari subtype specific variant | Cas5h | YES | TIGR02592 (HMM): CRISPR-associated protein Cas5, subtype I-B/HMARI | |
| Cas6, Hmari region | Cas6 | YES | TIGR01877 (HMM-CLUST): CRISPR-associated endoribonuclease Cas6 | |
| Csh1 family, TIGR02591 | Csh1 | YES | TIGR02591 (HMM): CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI | |
| Csh2 family, TIGR02590 | Csh2 | YES | TIGR02590 (HMM): CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI | |
| Accession | Name |
|---|
| GenProp0310 | CRISPR system, I-F/Ypest subtype |
| GenProp0313 | CRISPR system, I-C/Dvulg subtype |
| GenProp0314 | CRISPR system, II/Nmeni subtype |
| GenProp0315 | CRISPR system, I-E/Ecoli subtype |
| GenProp0316 | CRISPR system, III-B/RAMP module subtype |
| GenProp0317 | CRISPR system, I-B subtype, Tneap branch |
| GenProp0318 | CRISPR system, III-A/Mtube subtype |
| GenProp0319 | CRISPR system, I-A/Apern subtype |
| GenProp0469 | CRISPR system, Dpsyc subtype |
| GenProp0670 | CRISPR system, Aferr subtype |
| GenProp0685 | CRISPR system, I-D/Cyano subtype |
| GenProp0768 | CRISPR system, Pging subtype |
| GenProp0922 | CRISPR system, Myxan subtype |
| GenProp1061 | CRISPR system, PreFran subtype |
