Genome Property Definition Page
Accession | GenProp0292 | |
Name | ethanolamine degradation organelle | |
Type | SYSTEM | |
Description | Ethanolamine can be broken down to acetaldehyde by the action of ethanolamine ammonia lyase, an adenosyl cobalamin (vitamin B12) dependent enzyme. In its simplest form this system consists only of the two subunits of the enzyme, but ususally also includes a transporter for ethanolamine and may include a coexpressed acetaldehyde dehydrogenase to ensure that the toxic aldehyde is efficiently converted to acetyl-CoA. This property encompasses the more complex version of this system which includes additional genes coding for the proteinaceous coat of a specialized organelle as well as other genes for the efficienct maintenance and regulation of the lyase, handling of the product and import of the substrate. Presumably, this organellar system in organisms which may rely on ethanolamine as a primary carbon source. | |
Parent Property | GenProp0294: ethanolamine degradation proteinaceous organelle | |
Literature References |
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Web References | Glycerophospholipid metabolism | |
Gene Ontology Term | GO:0046336: ethanolamine catabolic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
phosphotransacetylase | PtrnsAc | NO | PF01515 (HMM-CLUST): phosphate acetyl/butyryl transferase | GO:0046336: ethanolamine catabolic process |
conserved hypothetical in ethanolamine operon | eut-chp | NO | TIGR02536 (HMM): ethanolamine utilization protein | GO:0046336: ethanolamine catabolic process |
reactivating factor for ethanolamine ammonia lyase | eutA | YES | PF06277 (HMM): ethanolamine utilization protein EutA | GO:0046336: ethanolamine catabolic process |
ethanolamine ammonia lyase, large subunit | eutB | YES | PF06751 (HMM): ethanolamine ammonia-lyase, large subunit | GO:0046336: ethanolamine catabolic process |
ethanolamine ammonia lyase, small subunit | eutC | YES | PF05985 (HMM): ethanolamine ammonia-lyase, light subunit | GO:0046336: ethanolamine catabolic process |
acetaldehyde dehydrogenase (acetylating) | eutE | YES | TIGR02518 (HMM-CLUST): acetaldehyde dehydrogenase (acetylating) PF00171 (HMM-CLUST): aldehyde dehydrogenase (NAD) family protein PF00171 (NOCLUST): aldehyde dehydrogenase (NAD) family protein | GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process |
alcohol dehydrogenase, ethanolamine operon related | eutG | YES | PF00465 (HMM-CLUST): alcohol dehydrogenase, iron-containing | GO:0046336: ethanolamine catabolic process |
ethanolamine permease | eutH | YES | TIGR00908 (HMM): ethanolamine permease PF04346 (HMM): ethanolamine utilisation protein EutH | GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process |
ethanolamine utilization protein EutJ | eutJ | NO | TIGR02529 (HMM): ethanolamine utilization protein EutJ family protein | GO:0046336: ethanolamine catabolic process |
microcompartment coat protein | eutM | YES | PF00936 (HMM-CLUST): BMC domain | GO:0046336: ethanolamine catabolic process |
carboxysome coat protein homolog | eutN | YES | PF03319 (HMM-CLUST): ethanolamine utilisation protein EutN/carboxysome | GO:0046336: ethanolamine catabolic process |
ethanolamine utilization protein, EutP | eutP | NO | TIGR02528 (HMM-CLUST): ethanolamine utilization protein, EutP | GO:0046336: ethanolamine catabolic process |
ethanolamine utilization protein, PduL homolog | eutPduL | NO | PF06130 (HMM-CLUST): propanediol utilization protein PduL | GO:0046336: ethanolamine catabolic process |
carboxysome coat protein homolog | eutPduT | NO | TIGR02526 (HMM): PduT-like ethanolamine utilization protein | GO:0046336: ethanolamine catabolic process |
ethanolamine utilization protein, EutQ | eutQ | NO | PF06249 (HMM-CLUST): ethanolamine utilization protein EutQ | GO:0046336: ethanolamine catabolic process |
cob(I)alamin adenosyltransferase | eutT | NO | PF01923 (HMM-CLUST): putative ATP:cob(I)alamin adenosyltransferase | GO:0046336: ethanolamine catabolic process |
regulatory components | regul | NO | PF00007 (HMM-CLUST): cystine-knot domain PF07568 (HMM-CLUST): histidine kinase PF00072 (HMM-CLUST): response regulator receiver domain PF00165 (HMM-CLUST): transcriptional regulator, AraC family | GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process |
Parent Properties
Accession | Name |
---|---|
GenProp0294 | ethanolamine degradation proteinaceous organelle |