Genome Property Definition Page
| Accession | GenProp0288 | |
| Name | tetrahydromethanopterin S-methyltransferase complex | |
| Type | SYSTEM | |
| Description | This complex of eight subunits, MtrA-H, effects the transfer of a methyl froup from tetrahydromethanopterin to coenzyme M using a cobalamin (B12) cofactor residing on MtrA. This transfer is coupled to an energy-driven sodium-ion pump. Methane is subsequently released by a two-electron reduction of the methyl-coenzyme M by the enzyme methyl-coenzyme M reductase. | |
| Parent Property | GenProp0011: methanogenesis GenProp0284: cobalamin-utilizing enzymes | |
| Literature References |
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Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| subunit A, cobalamin-containing | MtrA | YES | TIGR01111 (HMM): tetrahydromethanopterin S-methyltransferase, subunit A | |
| MtrB | YES | TIGR04166 (HMM): tetrahydromethanopterin S-methyltransferase, subunit B | ||
| MtrC | YES | TIGR01148 (HMM): tetrahydromethanopterin S-methyltransferase, subunit C | ||
| MtrD | YES | TIGR01112 (HMM): tetrahydromethanopterin S-methyltransferase, subunit D | ||
| MtrE | YES | TIGR01113 (HMM): tetrahydromethanopterin S-methyltransferase, subunit E | ||
| MtrF | YES | TIGR02507 (HMM): tetrahydromethanopterin S-methyltransferase, F subunit | ||
| MtrG | YES | TIGR01149 (HMM): tetrahydromethanopterin S-methyltransferase, subunit G | ||
| subunit H, pterin:cobalamin transferase | MtrH | YES | TIGR01114 (HMM): N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0011 | methanogenesis |
| GenProp0284 | cobalamin-utilizing enzymes |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0719 | methyl-coenzyme M reductase |
| GenProp0722 | methanogenesis marker set |
| GenProp0290 | class II (B12-dependent) ribonucleotide reductase |
| GenProp0294 | ethanolamine degradation proteinaceous organelle |