Genome Property Definition Page

AccessionGenProp0264
Nameglucosylglycerol biosynthesis
TypePATHWAY
DescriptionGlucosylglycerol is an osmolyte, a solute compatible with biological function inside cells that serves as an osmoprotectant. Other osmolytes include trehalose, sucrose, and glycine betaine and other betaines. Betaines offer stronger osmoprotection than glucosylglycerol but are nitrogen-requiring. The key enzyme, glucosylglycerol-phosphate synthase, uses ADP-glucose + sn-glycerol 3-phosphate. Glucose-1-phosphate adenylyltransferase, which synthesizes ADP-glucose, is therefore included in this property although it also has other roles, such as in glycogen biosynthesis.
JCVI RoleAdaptations to atypical conditions
Parent PropertyGenProp0267: osmolyte biosynthesis
GenProp0795: carbohydrate biosynthesis
Literature References
[ 1 ]Marin K, Zuther E, Kerstan T, Kunert A, Hagemann M  The ggpS gene from Synechocystis sp. strain PCC 6803 encoding glucosyl-glycerol-phosphate synthase is involved in osmolyte synthesis.  J Bacteriol 1998 Sep;180(18):4843-9.  PMID 9733686
Gene Ontology TermGO:0006970: response to osmotic stress (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
glucose-1-phosphate adenylyltransferaseADPglucYESTIGR02091 (HMM): glucose-1-phosphate adenylyltransferaseGO:0006970: response to osmotic stress
glucosylglycerol 3-phosphatasePaseYESTIGR02399 (HMM): glucosylglycerol 3-phosphataseGO:0006970: response to osmotic stress
glucosylglycerol-phosphate synthasesynthYESTIGR02398 (HMM): glucosylglycerol-phosphate synthaseGO:0006970: response to osmotic stress

Parent Properties
AccessionName
GenProp0267osmolyte biosynthesis
GenProp0795carbohydrate biosynthesis


Sibling Properties
AccessionName
GenProp0147glycine betaine biosynthesis from choline
GenProp0265trehalose biosynthesis, OtsAB pathway
GenProp0266trehalose biosynthesis, TreYZ pathway
GenProp0268ectoine biosynthesis
GenProp0281mannosylglycerate biosynthesis
GenProp0878N(epsilon)-acetyl-beta-lysine biosynthesis
GenProp1070beta-glutamate biosynthesis
GenProp0183dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
GenProp0297lipopolysaccharide biosynthesis
GenProp0750UDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate
GenProp0766anhydro-N-acetylmuramic acid to N-acetylglucosamine-phosphate
GenProp0793CMP-N-acetylneuraminate biosynthesis from UDP-N-acetylglucosamine
GenProp0794proposed N-acetyl sugar amidation module WbuXYZ
GenProp0796CMP-pseudaminic acid biosynthesis from UDP-N-acetylglucosamine
GenProp0811S-layer homology domain-mediated cell wall binding