Genome Property Definition Page

AccessionGenProp0238
Name2-aminoethylphosphonate catabolism to acetaldehyde
TypePATHWAY
DescriptionThe enzyme 2-aminoethylphosphonate--pyruvate transaminase (PhnW, EC 2.6.1.37) interconverts 2-aminoethylphosphonate plus pyruvate with 2-phosphonoacetaldehyde plus alanine. The enzyme phosphonoacetaldehyde hydrolase, a HAD superfamily hydrolase, breaks the C-P bond, yielding acetaldehyde plus inorganic phosphate. In species that appear to encode a phosphonate ABC transporter, this property is likely to be present only when the large phosphonate operon proposed to encode a multisubunit C-P lyase, as found in Escherichia coli, is not found.
JCVI RolePhosphorus compounds
Parent PropertyGenProp0142: catabolism
GenProp0720: 2-aminoethylphosphonate utilization
Literature References
[ 1 ]Kim AD, Baker AS, Dunaway-Mariano D, Metcalf WW, Wanner BL, Martin BM  The 2-aminoethylphosphonate-specific transaminase of the 2-aminoethylphosphonate degradation pathway.  J Bacteriol 2002 Aug;184(15):4134-40.  PMID 12107130
Web ReferencesAminophosphonate metabolism
Gene Ontology TermGO:0019635: 2-aminoethylphosphonate catabolic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
2-aminoethylphosphonate--pyruvate transaminasephnWYESTIGR02326 (HMM): 2-aminoethylphosphonate--pyruvate transaminaseGO:0019635: 2-aminoethylphosphonate catabolic process
phosphonoacetaldehyde hydrolasephnXYESTIGR01422 (HMM): phosphonoacetaldehyde hydrolaseGO:0019635: 2-aminoethylphosphonate catabolic process

Parent Properties
AccessionName
GenProp0142catabolism
GenProp07202-aminoethylphosphonate utilization


Sibling Properties
AccessionName
GenProp0055polyhydroxyalkanoic acids
GenProp0141galactose-6-phosphate degradation via tagatose-6-phosphate
GenProp0156cyanophycin-like storage polymers
GenProp0168glycogen system
GenProp0210phenylacetic acid catabolism
GenProp02314-hydroxyphenylacetate degradation
GenProp0233GABA utilization
GenProp0239propionyl-CoA catabolism
GenProp0241phosphonate catabolism
GenProp0271trehalose utilization
GenProp0272pyruvate fermentation to acetoin
GenProp0273protocatechuate degradation to beta-ketoadipate
GenProp0283beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA
GenProp0294ethanolamine degradation proteinaceous organelle
GenProp0457rhamnose catabolism
GenProp0458fucose catabolism
GenProp0461utilization of deoxynucleosides
GenProp0653ectoine catabolism
GenProp0674malonate decarboxylase
GenProp0686allantoin catabolism to glyoxalate and urea
GenProp0687allantoin catabolism to oxamate and carbamoyl-phosphate
GenProp0688urate catabolism to allantoin
GenProp0691glycolysis
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp0700purine catabolism via urate, xanthine and allantoin
GenProp0702benzoyl-CoA reductase
GenProp07034-hydroxybenzoyl-CoA reductase
GenProp0706cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway
GenProp0708catechol meta-cleavage pathway
GenProp0709benzoate catabolism BoxABC pathway
GenProp0711catechol ortho-cleavage upper pathway
GenProp0714galactarate utilization via tartronate semi-aldehyde
GenProp0715galactarate utilization via 2-oxoglutarate semialdehyde
GenProp0716glucarate utilization via tartronate semi-aldehyde
GenProp0717glucarate utilization via 2-oxoglutarate semialdehyde
GenProp0718oxalate degradation
GenProp0734amino acid catabolism
GenProp0749choline sulfate utilization
GenProp0760putrescine degradation to GABA via gamma-glutamylation
GenProp0763nicotinate fermentation to pyruvate and propionate
GenProp0810encapsulin proteinaceous organelle
GenProp0813pyrimidine utilization operon, RutABCDEFGR
GenProp0902quinohemoprotein amine dehydrogenase
GenProp1071myo-inositol catabolism
GenProp1072cyanase system
GenProp1076choline TMA-lyase system
GenProp07132-aminoethylphosphonate catabolism via phosphonoacetate