Genome Property Definition Page
| Accession | GenProp0139 |
| Name | degradation of tyrosine via homogentisate |
| Type | PATHWAY |
| JCVI Role | Amino acids and amines |
| Parent Property | GenProp0734: amino acid catabolism |
| Web References | KEGG: Tyrosine metabolism |
| Gene Ontology Term | GO:0019445: tyrosine catabolic process to fumarate (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| fumarylacetoacetase | Fah | YES | TIGR01266 (HMM): fumarylacetoacetase PF01557 (HMM-CLUST): fumarylacetoacetate hydrolase family protein | GO:0019445: tyrosine catabolic process to fumarate GO:0019445: tyrosine catabolic process to fumarate |
| homogentisate 1,2-dioxygenase | HmgA | YES | TIGR01015 (HMM): homogentisate 1,2-dioxygenase PF04209 (HMM): homogentisate 1,2-dioxygenase | GO:0019445: tyrosine catabolic process to fumarate GO:0019445: tyrosine catabolic process to fumarate |
| 4-hydroxyphenylpyruvate dioxygenase | Hpd | YES | TIGR01263 (HMM): 4-hydroxyphenylpyruvate dioxygenase | GO:0019445: tyrosine catabolic process to fumarate |
| maleylacetoacetate isomerase | Mai | YES | TIGR01262 (HMM): maleylacetoacetate isomerase | GO:0019445: tyrosine catabolic process to fumarate |
| tyrosine transaminase | TyrB | NO | TIGR01264 (HMM): tyrosine aminotransferase | GO:0019445: tyrosine catabolic process to fumarate |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0734 | amino acid catabolism |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0145 | histidine degradation to glutamate |
| GenProp0309 | arginine catabolism to glutamate via arginine succinyltransferase (AST) |
| GenProp0456 | attenuation system: tryptophanase |
| GenProp0639 | arginine degradation via citrulline, ATP-generating |
| GenProp0659 | tryptophan degradation to anthranilate |